To provide fast-track formulation services, the new ‘Closer to the Formulator’ (C2F) centre offers DFE Pharma’s excipient expertise to help pharmaceutical companies achieve ‘first-time right’ formulations.
DFE Pharma, a global leader in pharma- and nutraceutical excipient solutions, today announced the launch of its new Centre of Excellence “Closer to the Formulator” (C2F) in Hyderabad, India. The C2F centre is based in Genome Valley, a hub of major Indian and global (bio)pharmaceutical companies and renowned research organisations. C2F helps pharmaceutical companies to shorten the time from a concept to a finished commercial product through expertise in all phases of pharmaceutical development.
Pharmaceutical companies face increasing challenges, such as developing robust formulations which can be scaled up for high-speed production and first launched in the market. Smooth regulatory processes depend on decisions made in the development phase. ‘First-time right’ formulations are essential for success in the highly competitive market. Reducing cost and time of development can also allow affordable and new medicines to reach more patients, as advocated by national and regional policies such as the Jan Aushadi1 initiative in India or the EU pharmaceutical strategy.
“Our new 1200m2 C2F centre of excellence offers cutting-edge capabilities and resources to improve product development globally, while also integrating hardware and data management software,” explains Dr. Anilkumar S. Gandhi, Director of the C2F centre. “Our services result in robust formulations, utilising top-level excipient expertise transferrable to scale-up. We aim to further collaborate with our customers in this new centre to combine the joint formulation expertise.”
Specialising in oral solid dosage forms
The services offered by this new state-of-the-art facility are mainly focused on oral solid dosage forms, comprising all types of pre-registration work including development, scale-up, and technology transfer. Formulation support includes specialised dosage forms such as orally disintegrating, effervescent, chewable, and sublingual tablets, minitablets, etc. C2F capabilities also support efficiency projects such as conversion from wet granulation to direct compression.
The centre works with the active pharmaceutical ingredients (APIs) and can utilise innovative concepts with model APIs. The equipment covers an instrumented tablet press, an automated capsule filling machine, a tablet coater, a blister packaging machine, stability chambers, and state-of-the-art analytical equipment. The C2F offering can provide pharmaceutical companies with multiple advantages such as significantly lowering the number of development cycles, for example, and reducing formulation costs when launching a medicine.
Support for global pharma
Speaking about C2F, Martti Hedman, CEO of DFE Pharma added: “DFE Pharma has made a multimillion-euro investment in the new Center of Excellence in Hyderabad. Our overall goal is to help the global and Indian pharmaceutical industry to launch new products fast, at a low cost, and always first time-right. This new Center of Excellence demonstrates how DFE Pharma anticipates trends and innovations to increase patient’s access to safe, high-quality medicines.”
Honorable Minister Mr. K.T. Rama Rao, Cabinet Minister for IT, Industries & Commerce, Municipal Administration & Urban Departments of Telangana government (India) said: “I’m delighted to welcome DFE Pharma, a global leader in pharma- and nutraceutical excipient solutions in Genome Valley, Hyderabad. We are happy to support and facilitate the establishment of “Closer to the Formulator” (C2F) with the major objective of helping pharma companies to move up the value chain. The Government of Telangana will work with DFE Pharma to ensure that Life Sciences companies in the state leverage from this facility.”
The South African agent for DFE Pharma is IMCD SA.