Ongoing research on COVID-19 vaccines is key to controlling the pandemic

Continued research into the effectiveness of COVID-19 vaccines is imperative to prevent a worsening of the impact of COVID-19, says data and analytics company, GlobalData.  

Mohamed Abukar, MSc, clinical trials analyst at GlobalData, comments: “The fast-spreading new COVID-19 variants may reduce the protective effects offered by the leading vaccines. As a result, researchers need to ascertain whether the vaccines are as effective against the new viral variants or if they require some level of modification to yield optimum immune response against the variants.”

covid-19 vaccine Image by torstensimon from Pixabay
Continued research into the effectiveness of COVID-19 vaccines is imperative to prevent a worsening of the impact of COVID-19

US takes lead in research

The US takes the lead in research, accounting for 11.5% of the ongoing COVID-19 vaccine studies, with China following with 7.6%, narrowly outnumbering India at 7.3%. Germany is in fourth place with 4.6%; Brazil, the UK, and Australia are tied with 4.2% each.

The largest proportion of the ongoing vaccine trials are now in Phase II (38.6%) and Phase III (36.3%), after Phase I studies dominated the earlier period of the pandemic.

As clinical trials progress, more effectiveness results of vaccine candidates have become available. The first data released, for Moderna’s mRNA-1273 and Pfizer/BioNTech’s BNT162b2, displayed the highest efficacy levels of around 95%. These vaccines model the immune response around the spike protein.

Abukar continues: “Consequently, 87.1% of vaccines in the ongoing trials are now targeting the spike protein, demonstrating the high level of confidence obtained from the positive results of approved vaccine agents.”

Ongoing studies

BioNTech, Johnson & Johnson and Gamaleya are the top three trial sponsors, each with five ongoing studies. Novavax, the University of Oxford, Sinovac, Moderna, Cadila, and CureVac are each sponsoring four studies.

Abukar concludes: “A number of the listed top sponsors have already attained some level of approval for their vaccines and are continuing research to expand on knowledge of the efficacy and safety profiles of these agents. It is imperative that clinical research continues at the same pace to constantly evolve the current knowledge and adapt to new challenges such as new viral variants and ultimately to produce a universal vaccine.”



Latest


26 Feb 2021
Melcura HoneyGel revolutionises at-home wound care

Medika SA trading as the Melcura brand, a trusted and well-established wound care brand that has been based in hospitals…

Melcura HoneyGel revolutionises at-home wound care

Medika SA trading as the Melcura brand, a trusted and well-established wound care brand that has been based in hospitals for over 15 years, has finally launched online and at select local pharmacies. Melcura products are a crucial component in one’s arsenal for fast, complete wound healing when an accident…

25 Feb 2021
Environ is named Top Medical Skincare Line of the Decade

Environ Skin Care has won the award for Top Medical Skincare Line of the Decade. With a long list of…

Environ is named Top Medical Skincare Line of the Decade

Environ Skin Care has won the award for Top Medical Skincare Line of the Decade. With a long list of over 100 highly esteemed recognitions received for outstanding products worldwide, South African born, globally recognised professional brand Environ Skin Care has been on an international winning streak the past few…

25 Feb 2021
Adcock Ingram reports resilient trading performance despite COVID-19 challenges

The Adcock Ingram Group has achieved a 4% increase in turnover for the six month period to 31 December 2020.…

Adcock Ingram reports resilient trading performance despite COVID-19 challenges

The Adcock Ingram Group has achieved a 4% increase in turnover for the six month period to 31 December 2020. The company achieved these results despite challenging trading conditions caused by COVID-19, a depressed economy and decline in demand for certain categories of medicine and products. Performance metrics include: •         …

24 Feb 2021
Virtual conference drives the goal to buy Africa for Africa

The Made in Africa Conference and Expo will be the largest ever virtual gathering of and showcase of African buyers…

Virtual conference drives the goal to buy Africa for Africa

The Made in Africa Conference and Expo will be the largest ever virtual gathering of and showcase of African buyers and sellers, taking place on 13 and 14 April 2021.   With the COVID-19 pandemic pushing African nations to develop local solutions to the continent’s challenges, the time has come…


Top stories


25 Jun 2020
How to ensure business agility in a pandemic

BY: Neil Birch, CEO at Novus Holdings Business agility is the capability of a business to respond quickly to a…

How to ensure business agility in a pandemic

BY: Neil Birch, CEO at Novus Holdings Business agility is the capability of a business to respond quickly to a changing environment, whether it be internal or external. Qualities of agile businesses include being adaptive, flexible and creative in your response to change without losing momentum (remaining productive) or vision.…

01 May 2020
Fibertex manufactures critical components for COVID-19 PPE

Fibertex SA, part of the global Fibertex Nonwovens group, has developed versatile high-performance components for protective facemasks and respirators. “Fibertex,…

Fibertex manufactures critical components for COVID-19 PPE

Fibertex SA, part of the global Fibertex Nonwovens group, has developed versatile high-performance components for protective facemasks and respirators. “Fibertex, which continuously invests in technological advancements to meet requirements in diverse industries – has increased production capacity of materials so desperately needed during the global COVID-19 pandemic,” explains Rosa Naidoo,…

23 Apr 2020
Are you South Africa’s best female entrepreneur?

Entries are now open for the Santam Women of the Future Awards 2020 in association with Fairlady and True Love.…

Are you South Africa’s best female entrepreneur?

Entries are now open for the Santam Women of the Future Awards 2020 in association with Fairlady and True Love. Santam, Fairlady and, for the first time this year, Truelove Magazine, have partnered up in the search to find the best female entrepreneurs in the country. Best women entrepreneurs If…

30 Nov 2017
Rooibos could reduce risk of “Type 3” diabetes – a precursor to Alzheimer’s

Researchers at Warren Alpert Medical School at Brown University in the US found a link between a relatively new form…

Rooibos could reduce risk of “Type 3” diabetes – a precursor to Alzheimer’s

Researchers at Warren Alpert Medical School at Brown University in the US found a link between a relatively new form of diabetes, known as “type 3” diabetes and Alzheimer’s disease.


Visit the official COVID-19 government website to stay informed: sacoronavirus.co.za