New skin study highlights collagen peptide efficacy

The results of a double-blind, placebo-controlled clinical trial on collagen density in skin subsequent to Peptan intake, are detailed in a graph.

The first comprehensive scientific publication of research into the anti-ageing benefits of Peptan collagen peptides has just been released. Appearing first in the Journal of Cosmetic Dermatology, this paper takes to the next level the science behind collagen peptides used as a supplement for skin beauty. It reveals strong clinical evidence to prove Peptan’s ability to restructure the collagen network in deep skin layers. This represents a true breakthrough in skin anti-ageing science. The newly published data also presents the statistically significant effect of Peptan collagen peptides on skin hydration, explained by the stimulation of hyaluronic acid production.


A powerful anti-ager

This new compilation of skin health research was performed by leading dermatological institutes: Laboratory Cosderma and BIO-EC Laboratory in France and the Souken Laboratory in Japan. It features evidence from two double-blind, placebo-controlled clinical trials on Asian and Caucasian women with different skin types, backed by further ex vivo studies on skin tissue.

The clinical research showed that Peptan significantly decreased the fragmentation of collagen in the deep layer of the dermis by >18 per cent after four weeks and as much as >31 per cent after 12 weeks of intake. Peptan also significantly increased the density of collagen in the dermis by <nine per cent after four weeks of intake. Skin hydration increased by an impressive 28 per cent, counteracting the appearance of dry skin which typically occurs through ageing. The ex vivo studies demonstrated Peptan’s anti-ageing effects from a mechanistic point of view with key findings including its positive impact on the ability of fibroblasts to produce collagen fibres and glycosaminoglycans (GAGs) such as the moisture-trapping hyaluronic acid. 

Feedback from the experts

Commenting on the published data, Dr Jérôme Asserin of Cosderma says: ‘At Cosderma we specialise in the analysis of safety and efficacy of ingredients for the skin, ensuring a high level of scientific research quality and independence of the studies. The actual results for women who took the collagen peptide supplement show a real effect on restructuring the collagen network by decreasing fragmentation.’ 

Dr Elian Lati from the BIO-EC Laboratory adds: ‘The results delivered by Peptan collagen peptides within the skin tissue were real. There was a particularly high stimulation of GAGs such as hyaluronic acid. The ex vivo study provided important insights into the mechanisms of collagen peptides on tissue level which provide the basis for its skin anti-aging effects.’

Clear compelling evidence 

The review in the Journal of Cosmetic Dermatology provides the first-ever publication of data to show skin restructuring effects after taking a nutraceutical ingredient. This data is substantiated by a high level of scientific research and the only results to date to demonstrate the underlying mechanism of how collagen peptides help strengthen and rejuvenate the deeper skin layers. The results also show how it maintains the cohesive and dense collagen network that is key to preventing wrinkles and sagging.

The significant effect of Peptan collagen peptides on skin hydration is also noteworthy – as maintaining good hydration is crucial for smooth, plump skin and in preventing the formation of micro-relief wrinkles.

The paper also provides clear, compelling evidence to support the use of collagen peptides in ingestible ‘beauty from within’ products and gives manufacturers a proven ingredient solution when looking to enter the dynamic market of nutricosmetics.

A promising market

Peptan collagen peptides are safe, bioactive peptides, optimised through a careful hydrolysation process to make them easily digestible, highly bioavailable and able to promote specific benefits in the target tissue. Globally recognised as the preferred bioactive ingredient of leading nutricosmetic brands, Peptan is now benefiting from a notable increase in popularity in Western markets thanks to the growth of this market outside of Asia. Credible scientific research provides manufacturers of nutricosmetics with vital information when looking to create clear differentiation for their products in a competitive market place.



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