R&D collaboration advances treatment of immune mediated diseases

Lead Pharma, a clinical stage pharmaceutical company that designs and develops medicines for the treatment of immune mediated diseases and cancer, has entered into a collaboration and licence agreement with Roche to develop oral small molecules to treat a broad range of immune mediated diseases.

In this single target research collaboration Lead Pharma and Roche will collaborate in research activities up to the selection of a pre-clinical candidate after which Roche will be responsible for further development and global commercialisation.

Agreement Image by Gerd Altmann from Pixabay
Lead Pharma has entered into a collaboration and licence agreement with Roche to develop oral small molecules to treat a broad range of immune mediated diseases

Terms of the agreement

Under the terms of the agreement, Lead Pharma will receive an upfront payment of €10 million, and will be eligible to receive research funding and pre-clinical milestone payments; total potential payments including research, development, regulatory and sales milestones may add up to an aggregate of €260 million, plus royalties on worldwide sales.

“Our ambition is to develop life-changing treatments for patients. We are delighted to team up with Roche to pursue this goal,” says Frans van den Berg, chief executive officer of Lead Pharma. “Partnering is a key element of our strategy, this collaboration is yet another validation of the value of Lead Pharma’s innovation power.”

Arthur Oubrie, chief scientific officer of Lead Pharma, added: “This is the second project we partner with one of the largest pharmaceutical companies under our Discover, Design and Deliver platform. Our rigorous target selection process, translational screening cascade, and smart medicinal chemistry have been essential to bring this project to this stage. We are keen to collaborate with our colleagues at Roche to bring this novel approach to patients.”

“We are committed to advancing innovative science and transformative medicines for people affected by different immune mediated diseases,” says James Sabry, global head, Roche Pharma Partnering. “We are looking forward to further building on our expertise in this field and collaborating with Lead Pharma, aiming to make a difference for those patients.”



Latest


03 Dec 2020
GELITA acquires majority shares in Turkish gelatine producer

GELITA has acquired 65% of shares in Turkish gelatine producer, SelJel. With this Joint Venture, GELITA is further strengthening its…

GELITA acquires majority shares in Turkish gelatine producer

GELITA has acquired 65% of shares in Turkish gelatine producer, SelJel. With this Joint Venture, GELITA is further strengthening its position as the industry’s global leader. The remaining 35% of the shares remain with the founding family Tezman. Halal status With approximately 6 500 metric tons of edible, pharmaceutical and…

03 Dec 2020
Here’s how much SA companies spent on corporate social investment in 2020

South African companies spent an estimated R10.7 billion on corporate social investment (CSI) in the 2020 financial year. This represents…

Here’s how much SA companies spent on corporate social investment in 2020

South African companies spent an estimated R10.7 billion on corporate social investment (CSI) in the 2020 financial year. This represents a marginal 1.2% growth in real terms from R10.2 billion in 2019, according to CSI consultancy Trialogue. The research was published in the latest Trialogue Business in Society Handbook, released…

02 Dec 2020
How to thrive as the labelling industry goes digital

To help label converters try to understand how they can take the first step into their digital journey, HP is…

How to thrive as the labelling industry goes digital

To help label converters try to understand how they can take the first step into their digital journey, HP is releasing a new eBook: Outrun the Future. The Time is Now. How to thrive as the label industry goes digital. 2020 has brought about significant changes in the way we…

02 Dec 2020
New countertop dishwasher washes more dishes using less water in half the time

BASF and Heatworks, a US-based tech firm, have partnered to support the further development of the award-winning Tetra countertop dishwasher…

New countertop dishwasher washes more dishes using less water in half the time

BASF and Heatworks, a US-based tech firm, have partnered to support the further development of the award-winning Tetra countertop dishwasher with regard to its cleaning performance. While Heatworks is using its patented Ohmic Array Technology, BASF is supporting the development with its leading portfolio of sustainable products for the cleaning…


Top stories


25 Jun 2020
How to ensure business agility in a pandemic

BY: Neil Birch, CEO at Novus Holdings Business agility is the capability of a business to respond quickly to a…

How to ensure business agility in a pandemic

BY: Neil Birch, CEO at Novus Holdings Business agility is the capability of a business to respond quickly to a changing environment, whether it be internal or external. Qualities of agile businesses include being adaptive, flexible and creative in your response to change without losing momentum (remaining productive) or vision.…

01 May 2020
Fibertex manufactures critical components for COVID-19 PPE

Fibertex SA, part of the global Fibertex Nonwovens group, has developed versatile high-performance components for protective facemasks and respirators. “Fibertex,…

Fibertex manufactures critical components for COVID-19 PPE

Fibertex SA, part of the global Fibertex Nonwovens group, has developed versatile high-performance components for protective facemasks and respirators. “Fibertex, which continuously invests in technological advancements to meet requirements in diverse industries – has increased production capacity of materials so desperately needed during the global COVID-19 pandemic,” explains Rosa Naidoo,…

23 Apr 2020
Are you South Africa’s best female entrepreneur?

Entries are now open for the Santam Women of the Future Awards 2020 in association with Fairlady and True Love.…

Are you South Africa’s best female entrepreneur?

Entries are now open for the Santam Women of the Future Awards 2020 in association with Fairlady and True Love. Santam, Fairlady and, for the first time this year, Truelove Magazine, have partnered up in the search to find the best female entrepreneurs in the country. Best women entrepreneurs If…

30 Nov 2017
Rooibos could reduce risk of “Type 3” diabetes – a precursor to Alzheimer’s

Researchers at Warren Alpert Medical School at Brown University in the US found a link between a relatively new form…

Rooibos could reduce risk of “Type 3” diabetes – a precursor to Alzheimer’s

Researchers at Warren Alpert Medical School at Brown University in the US found a link between a relatively new form of diabetes, known as “type 3” diabetes and Alzheimer’s disease.


Visit the official COVID-19 government website to stay informed: sacoronavirus.co.za