The release of the latest Thermo Scientific Orbitrap LC-MS/MS

Anatech Instruments, proud supplier of Thermo Scientific is excited to announce the release of the new Orbitrap-based Mass Spectrometer (MS).

 With the availibilty of the new Q Exactive Focus every laboratory can afford a LC-MS/MS. Laboratories performing food and environmental testing, clinical research, forensic toxicology, pharmaceutical/biopharmaceutical measurements, and other applied analyses can now benefit from the performance of high-resolution accurate-mass (HRAM) Orbitrap mass spectrometry designed for cost-per-sample-sensitive workflows. Thermo Scientific has found that small scale research labs also require the combination of screening and quantitative capabilities of the hybrid mass spectrometry in their labs, where cost per sample and time-to-results really matter.

 The new Thermo Scientific Q Exactive Focus LC-MS/MS is designed to make the qualitative and quantitative power of Orbitrap-based instruments available to customers who use quadrupole time-of-flight (Q-TOF) mass spectrometry or other technologies.  It combines high-performance quadrupole precursor ion selection with a HRAM Orbitrap mass analyzer, providing excellent mass accuracy, sensitivity and fast polarity switching. This has been shown to selectively and accurately quantify and confirm analytes with comparable sensitivity to triple quadrupole instruments.

  “The Q Exactive Focus system will rapidly become the gold standard because this single instrument will answer routine quantitative and research analytical demands at an affordable price,” stated Dr. Bertrand Rochat, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, a Q Exactive Focus early access user.

 According to early access user Dr. Hans Mol, RIKILT Wageninen UR, the Netherlands, the Q Exactive Focus is well suited for pesticide residue analysis. Besides comparable quantitative data for frequently detected compounds, this instrument provides a complementary screen of many other compounds from the same injection.

 The Q Exactive offers the following capabilities:

  • Selected ion monitoring (SIM), parallel reaction monitoring (PRM).
  • Data-independent acquisition (DIA).
  • Full scan confirmation mode and parallel reaction monitoring (PRM) are designed for targeted screening combined with reproducible quantitation results.
  • Data-independent acquisition (DIA) provides qualitative coverage for screening unknowns with supporting quantitative data for many of the unknowns identified.
  • Q Exactive Focus specification
  • Orbitrap analyzer
  • Mass Range m/z 50 – 2000
  • Mass Accuracy <1ppm
  • Max. Mass Resolution >70,000
  • Scan speed up to 12Hz MS and 12 Hz MS/MS
  • Polarity switching
  • Top 2  ddMS2
  • No Multiplexing
  • Refined workflows that are optimal for routine laboratories 

    The Q Exactive Focus mass spectrometer delivers qualitative and quantitative results every day and is an affordable option to all routine laboratories where performing identification, quantitation and confirmation is possible in one analysis.



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